The Rabbit Anti-Guanine nucleotide-binding protein-like 3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GNL3L. This antibody recognizes Human antigen. The Rabbit Anti-Guanine nucleotide-binding protein-like 3 Antibody has been validated for the following applications: EIA, Immunoassay, and ELISA.
Description
Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP